Heroin detox · Tarzana, CA
Heroin detox in Los Angeles, from the first hours to the months after.
Heroin detox in Los Angeles at Lumora Recovery is supervised withdrawal from heroin in a state-licensed residence in Tarzana. NIDA says withdrawal can begin within hours of the last use, peaks 24 to 48 hours later and eases after about a week. For anyone who injects, the assessment also asks about infection, because some infections need a hospital first.
What happens during heroin detox?
Heroin detox is the medically supervised period in which heroin clears the body and withdrawal is managed, as the first stage of treatment. SAMHSA’s detoxification guide describes it as evaluation, then stabilization, then preparing the person to enter treatment, and it says detox alone is not enough.
Heroin is an opioid made from morphine, which comes from the seed pod of the opium poppy. NIDA describes it as a white or brown powder or a sticky black substance known as black tar heroin. Used repeatedly, it produces tolerance, meaning more is needed for the same effect, and dependence, meaning the body reacts with withdrawal if use drops suddenly. NIDA also reports that repeated use changes the brain’s structure, including its white matter. The institute’s treatment principles place detox at the start of care, noting that by itself it rarely changes long-term use.
Last updated
Timeline
How long does heroin withdrawal last, in hours, days and months?
Heroin withdrawal usually starts within hours, is at its hardest over the first one to three days, and settles over roughly one to one and a half weeks, with sleep and mood sometimes lagging for months. Three federal sources describe it, each in slightly different terms, so here they are side by side.
| Stage | NIDA, heroin research report | MedlinePlus | SAMHSA TIP 63 (short-acting opioids) |
|---|---|---|---|
| First signs | Within a few hours of the last use | About 12 hours after the last heroin use | 8 to 24 hours after the last use |
| Hardest stretch | Major symptoms peak 24 to 48 hours after the last dose | Lists early and later symptoms without a peak time | Fully developed at 1 to 3 days |
| Easing | Major symptoms subside after about a week | No day count given | About 7 to 10 days for the acute course |
| Long tail | Some people show withdrawal signs for many months | Advises screening for depression during detox | Low mood, craving, poor sleep and pain sensitivity for weeks or months |
Typical ranges for groups of people, not a forecast for one person, and not a plan for stopping at home.
Why the three sources disagree a little. NIDA writes about heroin specifically. SAMHSA writes about all short-acting opioids as a group, which takes in pain pills with different patterns of use. MedlinePlus gives a single typical onset. All three describe ranges, and individual withdrawal shifts with how much was used, for how long, and what else was in the drug. Read together, the overlap is clear enough to plan around: the first day is the start, the second and third are usually the hardest, and the second week is usually easier. For methadone and pain pills compared side by side, see withdrawal timing for prescription opioids and methadone.
Symptoms
What are heroin withdrawal symptoms at each phase?
Heroin withdrawal symptoms move from restlessness and aching in the first hours to vomiting, diarrhea and cold flashes at the peak, and then to a long, quieter phase of poor sleep and low mood.
The first hours
MedlinePlus lists agitation, anxiety, muscle aches, watering eyes, a running nose, sweating, frequent yawning and trouble sleeping as the early signs.
The peak
NIDA describes restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumps, and involuntary leg movements. MedlinePlus adds stomach cramps, nausea and widened pupils. The medical risk in this phase is mostly about fluids: repeated vomiting and diarrhea can dehydrate a person, and vomit can be inhaled into the lungs.
The weeks and months after
As the physical symptoms fade, a different set can linger: broken sleep, low mood, craving and greater sensitivity to pain. MedlinePlus advises that people in detox be screened for depression and other mental illness.
Withdrawal from heroin is very unpleasant but, according to MedlinePlus, is not usually life threatening in itself. MedlinePlus is just as direct about what is: the biggest danger in opioid detox is going back to using, covered further down this page.
Injection health check
Which health problems from injecting heroin need a doctor before detox?
Infections of the heart valves, deep abscesses and blood-borne viruses are the injection-related problems most likely to need a doctor before or alongside detox. NIDA and MedlinePlus list them; the table below sets out what each one is and what a family can watch for or mention on the call.
| Problem | What it is | What to watch for or mention | Named by |
|---|---|---|---|
| Heart valve infection (endocarditis) | Inflammation of the heart’s inner lining and valves, usually from bacteria; unsterile needles let germs into the blood | Fever, chills, night sweats, tiredness, weight loss, breathlessness on effort, swollen feet or legs, painful spots on fingers or toes | MedlinePlus; NIDA |
| Skin abscesses and soft-tissue infections | Infections in the skin and the tissue beneath it | Any sore, swollen, hot or weeping area: describe it on the call | NIDA |
| Deep abscesses | Abscesses in the brain, lungs or kidneys | These are found by doctors, which is why unexplained fever matters | MedlinePlus |
| Scarred or collapsed veins | Damage to the veins used for injecting | Tells the assessing clinician how long and how often injecting has gone on | NIDA |
| Hepatitis B, hepatitis C and HIV | Viruses spread through shared needles, equipment or body fluids, which can pass to partners and children | Any past test result, or the fact that there has been no test | NIDA; MedlinePlus |
| Blocked blood vessels | Additives that do not dissolve can clog vessels leading to the lungs, liver, kidneys or brain | Part of the reason a full medical history matters | NIDA |
| Lung infections | NIDA links long-term heroin use, by any route, to pneumonia and tuberculosis | A cough, fever or breathlessness that is not getting better | NIDA |
For understanding only. Lumora does not diagnose these conditions on this page; the assessment decides whether a hospital or another doctor needs to come first.
Endocarditis, the one families most often miss
Endocarditis is easy to overlook, because sweating and tiredness also come with withdrawal. MedlinePlus lists intravenous drug use among its risk factors and names further signs: aches in muscles and joints, weakness, weight loss, tiny bleeds under the fingernails, and painful nodes on the fingers or toes. Its complications include brain abscess, heart failure and stroke.
MedlinePlus also notes that prompt treatment improves the outlook. So in someone who injects, fever with breathlessness or swelling is a reason to see a doctor quickly rather than wait until detox is over. If any of these signs are present, say so on the first call; the plan may start with a hospital.
The supply
Is heroin today mixed with fentanyl?
It can be, and there is no way to tell by looking. MedlinePlus says illegal heroin has no quality control and is sometimes mixed with fentanyl, and the CDC says illegally made fentanyl is added to heroin, often without the buyer knowing.
That changes three things for a family. First, an overdose may be harder to reverse: the CDC notes that stronger opioids such as fentanyl can need more than one dose of naloxone. Second, someone who believes they use only heroin may have built up a dependence on fentanyl too, which is worth telling the assessing clinician even as a guess. Third, MedlinePlus warns that heroin taken with prescription painkillers, other drugs or alcohol is very dangerous, and mixed supply makes those combinations harder to predict.
Street fentanyl can carry its own additives, including veterinary sedatives that naloxone does not reverse. Our fentanyl page explains xylazine, medetomidine and the other additives in street fentanyl.
If it happens
How do you recognize heroin overdose signs, and what do you tell 911?
A heroin overdose shows as slow or stopped breathing, tiny pupils, blue lips and a person who cannot be woken; the response is 911, naloxone if you have it, and staying with them. These six points draw on MedlinePlus and the CDC, and focus on what to do and say, and what to expect afterward.
Recognize it
Breathing that is slow, shallow, labored or absent. Pinpoint pupils, a discolored tongue, bluish lips and nails, a weak pulse. Drowsiness that slides into confusion or coma. MedlinePlus adds a simple test: the person does not wake to a loud voice or a firm rub on the breastbone.
Call 911
Call first, or have someone else call while you act. Poison Help, 1-800-222-1222, can also guide you, but an unresponsive person needs emergency services.
Give naloxone if you have it
MedlinePlus says bystanders can give naloxone to reverse a heroin overdose, and the CDC says it can restore breathing within two to three minutes. If fentanyl was in the heroin, more than one dose may be needed. How to give the nasal spray is set out in four steps below this list.
Do not make them vomit
MedlinePlus advises against inducing vomiting unless Poison Control or a health professional says to.
Have the facts ready
The person’s age, weight and condition; what they took, if known; how much; and when. These are the questions emergency services and Poison Help ask.
Stay, and expect a hospital
The CDC says to stay with the person until help arrives, or for at least four hours. MedlinePlus notes that even when an antidote works, recovery from an acute overdose takes 24 to 48 hours, and a hospital stay may follow because additives can damage organs, prolonged breathing trouble can lead to fluid in the lungs and pneumonia, and lying unconscious on a hard surface can cause crush injuries.
Giving naloxone nasal spray: four steps
These steps follow the MedlinePlus guide to naloxone nasal spray. Each device holds a single dose, and it does not need priming before use.
- Lay the person on their back, and support the back of their neck with your hand so the head tilts back.
- Put the tip of the nozzle into one nostril, until your fingers rest against the bottom of the nose, and press the plunger firmly.
- Turn the person onto their side, in the recovery position, and call 911 straight away if no one has yet.
- If they do not wake or breathe normally, or they wake and then slip back, give another dose with a new spray in the other nostril. Repeat every 2 to 3 minutes until emergency help arrives, and stay with them.
A common belief
Is smoking or snorting heroin safer than injecting?
Only in avoiding needle-borne infections. Heroin that is smoked or snorted still builds tolerance and dependence, still brings withdrawal when it stops, and still carries whatever was mixed into it, fentanyl included.
NIDA names this belief directly. Its research report on heroin says a misperception that purer heroin is safer, because it does not have to be injected, may be part of why people start. The tolerance and dependence NIDA describes come from repeated use, whatever the route.
The route also carries harms of its own. NIDA notes that snorting heroin can damage the tissue inside the nose and can perforate the nasal septum, the wall between the nostrils. Long-term heroin use, however it is taken, is linked to lung problems including pneumonia and tuberculosis, along with constipation, insomnia and changes to sexual function and menstrual cycles.
For detox, the route matters mainly for what the assessment looks for. Someone who has never injected avoids most of the infections in the table above. They do not avoid withdrawal, or the overdose risk that follows it.
Before the call
What should you tell admissions about heroin use?
Tell admissions how heroin is taken, when it was last used, any sign of infection, what else is used, any past overdose and how mood has been. None of it needs to be exact; each answer helps decide whether withdrawal can begin in the residence or should start in a hospital.
- How heroin is taken: injected, smoked or snortedInjecting brings the infection risks NIDA and MedlinePlus describe.
- Roughly when it was last usedIt places the person on the withdrawal timeline, which starts within hours.
- Fever, night sweats, breathlessness or swollen legsMedlinePlus lists these among the signs of a heart valve infection.
- Sores, swelling or redness near injection sitesNIDA names abscesses and soft-tissue infections as complications of injecting.
- Alcohol, benzodiazepines or pain pills as wellMedlinePlus calls these combinations very dangerous, and SAMHSA ties them to overdose.
- Past overdoses, especially any that needed more than one naloxone doseThe CDC notes that stronger opioids such as fentanyl can need repeat doses.
- Known hepatitis or HIV results, or noneNIDA links shared equipment to these viruses; it belongs in the medical history.
- Low mood, or any thought of suicideMedlinePlus advises depression screening in detox. 988 answers at any hour.
If a sedative such as Xanax or Klonopin is also used, do not cut it back without a prescriber; why that matters is set out in why benzodiazepines are never stopped suddenly.
Licensing and setting
Heroin detox in Los Angeles: a license on the public record, and how the setting is chosen
Lumora’s license is not something you have to take on our word. It sits in California’s public dataset of treatment facilities, kept by the Department of Health Care Services. The entry under 191642AP shows Lumora Recovery at 6130 Wilbur Avenue, licensed as a residential program that includes detoxification (RES-DETOX), with capacity for six residents and incidental medical services marked as approved. That approval, available to licensed residences since 2016, allows set medical services under a licensed practitioner, among them medical histories, health monitoring and the treatment of substance use disorders, detox included. It does not reach general primary care or anything that must be done in a licensed health facility. Find Lumora’s entry in the state’s facility data.
For heroin, the assessment looks hardest at three things: how the drug is taken, any sign of infection, and what else is used alongside it. Together they settle whether withdrawal begins in the house in Tarzana or in a hospital, with Lumora afterward if that fits. When a hospital should come first, admissions tells you on the call. For the wider picture, see how Lumora approaches detox across substances.
We work with many PPO plans, and admissions checks detox and residential benefits by phone. For the rules behind coverage, read the way PPO benefits for detox and rehab are decided.
After the medical phase
What comes after heroin detox?
Treatment for the opioid use disorder itself comes next, because detox ends withdrawal but not addiction, and the weeks that follow carry the highest overdose risk.
MedlinePlus states that most opioid overdose deaths occur in people who have just detoxed, because tolerance has fallen; NIDA lists lowered tolerance after a period without opioids as an overdose risk factor. SAMHSA’s expert panel goes further, advising against short-term supervised withdrawal as a treatment on its own, since most people who stop there return to use. Why the weeks after discharge carry that risk is set out in leaving opioid treatment without losing ground to overdose.
NIDA says medicines reduce craving and withdrawal and are most effective when paired with behavioral therapy. The FDA has approved three for opioid use disorder: methadone, which is dispensed only through certified opioid treatment programs; buprenorphine; and naltrexone, which can only begin once a person is fully off opioids. NIDA reports that people receiving methadone or buprenorphine are less likely to overdose or die. The choice, and its timing, belongs to the person and their treating clinician.
If residential treatment fits once withdrawal is over, it begins in the same house, with no transfer. Our page on heroin rehab once withdrawal is over explains that stage, including the health checks that follow injection use, and residential treatment for heroin and other opioid addiction covers the California rules on medication in licensed programs.
Plain definitions
What do the medical words around heroin detox mean?
Three terms a family is likely to hear during heroin detox, each defined in a sentence or two from the federal sources on this page.
Black tar heroin. A sticky, dark form of heroin, as opposed to the white or brown powder, according to NIDA. The form does not change the withdrawal.
Opioid use disorder. The clinical name for opioid addiction. NIDA describes medicines and behavioral therapy as treatments that are most effective in combination.
Protracted withdrawal. The long tail after the acute days: low mood, craving, poor sleep and heightened pain that SAMHSA says can last weeks or months.
Safety first
Cannot wake them, breathing slow or stopped: call 911.
Call 911, give naloxone if it is on hand, and stay. Do not try to make the person vomit. Poison Help at 1-800-222-1222 can advise, but emergency services come first. For fever with breathlessness in someone who injects, get medical care promptly. If someone close to you is in crisis or thinking of suicide, call or text 988 to reach the Suicide and Crisis Lifeline, open around the clock.
FAQ
Questions families ask
How soon does heroin withdrawal start?
Within a few hours of the last use, according to NIDA. MedlinePlus gives about 12 hours, and SAMHSA’s range for short-acting opioids is 8 to 24 hours. The first signs are usually restlessness, aching, a running nose, yawning and sweating.
When is heroin withdrawal at its worst?
NIDA says the major symptoms peak 24 to 48 hours after the last dose. SAMHSA describes withdrawal from short-acting opioids as fully developed at one to three days. Vomiting and diarrhea tend to be heaviest in that window, which is when fluids matter most.
Why can sleep and mood stay off for months after heroin?
NIDA notes that some people show withdrawal signs for many months, and SAMHSA describes a protracted phase of low mood, craving, poor sleep and pain sensitivity lasting weeks or months. It is common and is one reason treatment continues after detox.
Is street heroin mixed with fentanyl?
It can be. MedlinePlus says illegal heroin has no quality control and is sometimes mixed with fentanyl, and the CDC says many people do not know their drugs contain it. Neither the look nor the taste of heroin gives fentanyl away.
Does smoking or snorting heroin avoid the risks of injecting?
It avoids needle infections, not addiction, withdrawal or overdose. NIDA names the belief that heroin is safer when it is not injected as one reason people start. Snorting can also damage the nose and even make a hole in the wall between the nostrils.
What infections are linked to injecting heroin?
NIDA and MedlinePlus list infections of the heart valves and blood vessels, skin abscesses and soft-tissue infections, abscesses in the brain, lungs and kidneys, and hepatitis B, hepatitis C and HIV from shared needles or equipment.
What are the warning signs of a heart valve infection?
MedlinePlus lists fever, chills and sweats that are often worse at night, tiredness, weight loss, aches, shortness of breath on activity, and swelling of the feet, legs or belly. In someone who injects, these signs need a doctor promptly.
What are the signs of a heroin overdose?
Breathing that is slow, shallow, labored or stopped; tiny pupils; bluish lips and fingernails; a weak pulse; and drowsiness that turns into confusion or unresponsiveness. Call 911 straight away and give naloxone if you have it.
What should I tell 911 or Poison Help during a heroin overdose?
MedlinePlus suggests having the person’s age, weight and condition ready, along with what they took, how much and when. Poison Help is 1-800-222-1222. Do not make the person vomit unless a professional tells you to.
Can heroin withdrawal cause dehydration?
Yes. MedlinePlus notes that the vomiting and diarrhea of opioid withdrawal can dehydrate a person, and that vomit can be breathed into the lungs. Being unable to keep fluids down is a reason for medical care.
Other ways we help
Care at Lumora
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Medical Detox
Medically supervised withdrawal in the residence, leading straight into residential treatment.
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Residential Treatment
Living at Lumora for the length of the program, rather than going home each night.
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Dual Diagnosis Care
Mental health conditions that occur with substance use, treated together with it.
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Eating Disorder Support
Coordinated planning for eating disorders alongside substance use, including referral when that is safer.
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Aftercare Planning
A plan for life after Lumora, pointing to PHP, IOP, outpatient care, sober living or therapy near home.
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Tour the Residence
Bedrooms, lounges, the wellness room and the garden, photographed as they are.
Sources
- National Institute on Drug Abuse, Heroin
- National Institute on Drug Abuse, Heroin Research Report: Overview
- National Institute on Drug Abuse, Heroin Research Report: What are the long-term effects of heroin use?
- National Institute on Drug Abuse, Heroin Research Report: What are the medical complications of chronic heroin use?
- National Institute on Drug Abuse, Medications for opioid use disorder
- National Institute on Drug Abuse, Overdose prevention education for clinicians
- National Institute on Drug Abuse, Principles of Drug Addiction Treatment
- MedlinePlus, Heroin overdose
- MedlinePlus, Endocarditis
- MedlinePlus, Opiate and opioid withdrawal
- MedlinePlus, Naloxone nasal spray
- SAMHSA, TIP 63: Medications for Opioid Use Disorder (2021)
- SAMHSA, Detoxification and Substance Abuse Treatment (TIP 45 quick guide)
- CDC, Fentanyl (Overdose Prevention, 2025)
- CDC, Lifesaving naloxone (2025)
- California DHCS, Incidental Medical Services
- California DHCS, SUD Recovery Treatment Facilities (state facility record)
- 988 Suicide and Crisis Lifeline
This page is for information and is not a substitute for medical, legal or insurance advice. Sources checked October 10, 2026.
Admissions, 24 hours a day
Heroin detox in Los Angeles starts with a frank first call.
Call at any hour. Describe how heroin is used and anything else in the picture, and admissions will tell you whether withdrawal can begin at Lumora or should start in a hospital.